Co-injection integrated three transgenes that express from the mouse H-2Kb (MHC Class I) promoter: 1) human CuZn superoxide dismutase (SOD1) tagged with a hemagglutinin epitope tag; 2) human extracellular superoxide dismutase (SOD3) modified to include a glycosyl phosphatidylinositol (GPI) membrane linkage signal & tagged with a FLAG epitope tag; 3) human cellular glutathione peroxidase (Gpx-1) tagged with a histidine (6xHis) tag. (J:100091)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count