Co-injection integrated three transgenes that express from the mouse H-2Kb (MHC Class I) promoter: 1) human CuZn superoxide dismutase (SOD1) tagged with a hemagglutinin epitope tag; 2) human extracellular superoxide dismutase (SOD3) modified to include a glycosyl phosphatidylinositol (GPI) membrane linkage signal & tagged with a FLAG epitope tag; 3) human cellular glutathione peroxidase (Gpx-1) tagged with a histidine (6xHis) tag. (J:100091)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6)F1
--
Insertion
--
3
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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