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The M2rtTA tet transactivator is expressed in the epithelium of the intestine and colon under the control of the intestine-specific A33 promoter. The expression/activety of the transactivator is mosaic, most likely due to stochastic transgene silencing. Approximately 1 to 5 crypts in the proximal small intestine express the transgene, fewer in the distal intestine and colon. (J:104190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
