Log In|Sign Up
EN
CRISPR/Cas12a technology generated a C to T change resulting in an arginine to cysteine substitution at amino acid 1540 (p.R1540C). This corresponds to the p.R1537C variant carried in Neanderthals and Denisovans, extinct hominins close to modern humans. (J:343594)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
