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A human involucrin promoter drives expression of a Slc27a4 (Fatp4) cDNA (Fatp4) carrying two amino acid substitutions, S247G and T249G. Altering these critical residues inhibits acyl-CoA synthetase activity. Three lines were generated including 6, 7 and 11. (J:122660)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
