The transgenic construct contains the mouse Itgax (integrin alpha X or Cd11c) promoter directing expression of the endogenous mouse H2-Ab1 gene (I-A(b)) cDNA. Founder line 1 had 90% expression of MHC class II on dendritic cells. (J:169793)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count