CRISPR/Cas9 technology introduced a C to A change resulting in an arginine to serine substitution at amino acid 136 (p.R136S) in the inserted human APOE isoform 4 of the Apoetm3(APOE_i4)Yhg allele. (J:343279)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count