The targeting vector is designed to insert a loxP site upstream of exon 3, and a FRT-flanked PGK-neomycin cassette followed by a loxP-site upstream of exon 4. Flp-mediated recombination removed the neo cassette. (J:257103)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count