The targeting construct floxed exon 3 through the coding sequence in exon 4. Flp-mediated recombination removed the selection cassette inserted into intron 2. (J:310650)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count