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A cDNA encoding murine Prnp with an internal deletion of sequences encoding residues 105-125 was placed under the control of a construct containing a Prnp promoter with an expression pattern similar to that of endogenous PrP, with the exception that there is no expression in cerebellar Purkinje cells. (J:82809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
