The targeting construct inserted the -mCherry-(IRES)-CreERT2 followed by loxP flanked neo cassette into the exon 27 of the Prom1 gene just in front of the stop codon. The neomycin selection cassette was excised in vivo by crossing to cre-deleter. (J:343157)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count