Log In|Sign Up
EN
Intron 10 was targeted with two sgRNAs using CRISPR/Cas9 technology, resulting in a 268 bp deletion (GRCm39:chr17:27178158-27178425). This deletion eliminates the alternative 3' splice acceptor site that is used for NMD-mediated transcriptional regulation. (J:334714)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
