CRISPR/cas9 mediated recombination in zygotes from a cross of females homozygous for Atg16l1tm1c(EUCOMM)Wtsi and males homozygous for Atg16l1tm1c(EUCOMM)Wtsi and carrying Tg(Vil1-cre)997Gum> created a 2 nucleotide insertion of AT after the third codon resulting in a frameshift and premature stop at amino acid position 30. (J:340266)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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