A conditional allele was generated by flanking a critical exon(s) with loxP sites (further molecular details are not specified). Flp-mediated recombination removed a co-inserted selection cassette. Cre-mediated recombination removed the floxed exon(s) in the germline. (J:343009)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count