The targeting construct floxed exon 1. Flp-mediated recombination removed the FRT flanked neomycin resistance cassette inserted into intron 1. Cre-mediated recombination removed exon 1. (J:278550)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count