The targeting construct introduced a FAST (Flexible Accelerated STOP Tetracycline Operator (tetO)-knock-in) construct upstream of the endogenous ATG initiation site in exon 1. Flp-mediated recombination removed the neomycin resistance cassette. (J:338776)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count