ENU mutagenesis induced an undefined point mutation at GRCm38:chr1:40004864 that causes a missense mutation at glutamine codon (Q) 687 (CAG) (in ENSMUSP00000126961 and ENSMUSP00000141400; different coordinates in other isoforms) to either lysine (AAG) or glutamine (GAG). The mutation is implicated in altered T cell-dependent antibody responses to immunization. (J:217665)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count