ENU mutagenesis induced an undefined point mutation at GRCm38:chr1:40004864 that causes a missense mutation at glutamine codon (Q) 687 (CAG) (in ENSMUSP00000126961 and ENSMUSP00000141400; different coordinates in other isoforms) to either lysine (AAG) or glutamine (GAG). The mutation is implicated in altered T cell-dependent antibody responses to immunization. (J:217665)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
Single point
Recessive
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top