The targeting construct floxed exon 3 and placed an FRT-flanked neomycin resistance cassette upstream of the first loxP site. Flp-mediated recombination removed the selection cassette. (J:339458)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count