The targeting construct inserted a loxP site upstream of exon 3 and a floxed neomycin resistance cassette downstream of exon 4. Cre-mediated recombination removed exons 3 and 4, and the selection cassette. (J:342282)
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The targeting construct inserted a loxP site upstream of exon 3 and a floxed neomycin resistance cassette downstream of exon 4. Cre-mediated recombination removed exons 3 and 4, and the selection cassette. (J:342282)