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EN
A targeting vector is designed with (from 5' to 3') a ubiquitously expressed CAG promoter, a loxP-flanked stop cassette, a Venus reporter sequence, 3F2A (three tandem repeats of foot-and-mouth disease 2A peptide sequence) that mediates ribosomal skipping, the Apex2 gene sequence with a nuclear localization signal, a WPRE sequence, and an FRT-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette. (J:341917)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
