The targeting construct inserted upstream of exon 10 an FRT site, lacZ, loxP, neomycin resistance cassette, and FRT site. A second loxP site was inserted downstream of exon 10. Flp- and cre-mediated recombination removed the reporter, selection cassette, and exon 10. (J:341087)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count