Log In|Sign Up
EN
CRISPR-targeting of exon 3 inserted an Artificial Intron version 4 (AIv4) encoding a splice donor, essential intronic sequences flanked by loxP sites, and a splice acceptor site. Cre-mediated recombination removed the branch point and part of the polypyrimidine tract leaving a string of stop codons in all three frames. (J:342085)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
