An FRT-flanked PGK-neo cassette and a loxP site were inserted upstream of exon 2 and a second loxP site was inserted downstream of exon 5. The neomycin cassette was removed via flp-mediated recombination, leaving exons 2-5 floxed. (J:342039)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count