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A BAC clone containing the entire Lum gene, and where the endogenous translation initiation codon from the Lum gene was used to drive expression of CreERT2. The coding sequence in exon 2, as well as the splice donor site at the junction between exon 2 and intron 2 (50bp), was replaced with a cassette containing the open reading frame for CreERT2 and the Lum 3' untranslated region (UTR). A hGHpA (human Growth Hormone) polyadenylation signal was inserted 3 of the Lum 3UTR. (J:342042)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
