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The targeting construct inserted a floxed neomycin stop cassette, tTA, insulator, hCMV*1 promoter with a tetracycline responsive element, intron, human TREM2 with the mutation encoding the amino acid substitution arginine with histidine at position 47 (R47H) plus tagged with 5' HA and 3' triple FLAG tags, IRES, and EGFP reporter gene. (J:341604)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
