Exon 1 was flanked by loxP sites. An FRT-flanked neomycin cassette was inserted immediately at the 5 end of the second loxP site and a thymidine kinase cassette at the 3-end of exon 2. The neomycin selection cassette was removed via flp-mediated recombination. (J:297941)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count