The T2A-CreERT2 cassette was inserted immediately upstream of the endogenous stop codon in the exon 12 of the Mlc1 gene in frame. The FRT flanked Neo selection cassette was inserted 116 bp downstream of the 3' UTR. The Neo cassette in the targeting vector was removed during ES clone expansion. (J:341452)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129 x C57BL/6
Targeted
Insertion
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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