CreERT2 activity was induced by 4-hydroxytamoxifen to facilitate Cre-mediated insertion of the PAIR4 sequences into the lox71 site at the deletion point (117,126,667/116,237,220; mm9, Chr.12) of the Ightm4.2Mbu allele. The rox-flanked Actb-Bsd expression cassette was deleted after germline transmission. (J:341427)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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