The targeting construct inserted a loxP upstream of Mir183 and an F3-flanked neomycin resistance cassette with a 3' loxP site downstream of Mir182. Flp-mediated recombination removed the selection cassette and left the microRNA cluster floxed. (J:243640)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count