CRISPR/Cas9 technology targeting exon 2 generated three small deletion and one small insertion alleles. This record includes four alleles containing a 1-bp deletion, a 7-bp deletion, a 4-bp deletion, and a 2-bp insertion. No phenotypic differences are seen between these four mutant lines so they were combined and the pound symbol (#) is used because the lines are pooled. (J:338969)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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