A loxP site and neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 2. (J:335885)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count