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A targeting construct was generated in which exons 1 and 2 was flanked with loxP sites placed 2.6 kb upstream of exon 1 in the 5 UTR and 2.6 kb downstream of exon 2 within intron 2. For selection, a neomycin (Neo) cassette flanked by frt recombination sites was also inserted into intron 2. FLP-mediated recombination in the germline removed the neomycin cassette. (J:263909)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
