The allele is created using site-specific PhiC31 integrase-mediated transgenesis to insert a loxP-flanked stop cassette, Kozak sequences and the near-infrared emitting firefly luciferase derivative Akaluc directed by a chicken beta-actin promoter with a CMV enhancer (CAG promoter). Akaluc is a modified firefly luciferase (luc) containing 28 amino acid substitutions relative to luc. (J:341257)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
Targeted
Insertion
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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