The allele is created using site-specific PhiC31 integrase-mediated transgenesis to insert a loxP-flanked stop cassette, a Kozak sequence, the codon optimized firefly luciferase 2, and an SV40 polyA signal directed by a chicken beta-actin promoter with a CMV enhancer (CAG promoter). (J:341167)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count