The allele is created using site-specific PhiC31 integrase-mediated transgenesis to insert a loxP-flanked stop cassette, and the Antares-derived, orange-emitting, calcium-modulated bioluminescent indicator (CaMBI) followed by a polyA signal and directed by a chicken beta-actin promoter with a CMV enhancer (CAG promoter). CamBI 110 is composed of CyOFP1::N-terminal NLuc::1aa linker (I)::CaM::4aa linker (GGGS)::M13::2aa linker (EL)::C-terminal NLuc::CyOFP1. (J:341258)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
Targeted
Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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