Using CRISPR/Cas9 technology, two Lox2722 sequences were inserted to flank both E2 and E3 together in Igf1tm1Ispglline described in J:341100 in which the exon1 is flanked by LoxP sites and additionally includes a Neo cassette flanked by Frt sites. (J:341100)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count