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The targeting construct inserted a FRT neomycin resistance cassette in intron 21 and exon 22 was modified with an A to C point mutation encoding the amino acid substitution of glutamic acid with alanine at position 988 (E988A). Flp-mediated recombination removed the selection cassette. (J:340904)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
