The targeting construct inserted a loxP site upstream of exon 48, GFP reporter gene at the STOP codon, and FRT-flanked neomycin resistance cassette with 3' loxP site downstream of the 3' UTR. FLP-mediated recombination removed the selection cassette. (J:340902)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count