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The targeting construct consisting of an F3 site, a neomycin resistance cassette, CAG promoter, loxP-flanked transcriptional termination cassette, FLAG-HA tagged human GFAT1 open reading frame, human growth hormone polyadenylation signal and additional polyadenylation signal and FRT site were inserted into the locus. Upon cre-mediated recombination, the STOP cassette can be removed to get expression of the human GFAT1 under the control of the CAG promoter. (J:340718)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
