Using CRISPR-Cas9 technology, a T2A cleavable peptide and Cre recombinase was inserted downstream of the last exon (exon 4) in the Oprm1 gene. (J:340529)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count