A loxP site was inserted upstream of exon 4 and a loxP site and FRT-flanked neomycin selection cassette were inserted downstream of exon 5. The neomycin selection cassette was removed via flp-mediated recombination, leaving exons 4-5 floxed. (J:320936)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count