Exon 1 was replaced with an inducible cre ESR1 (ERT2) fusion followed by an FRT-flanked neo cassette. Flp-mediated recombination removed the selection cassette. (J:137426, J:237690)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count