LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank the exons 36 of the gene. FLP-mediated recombination resulted in the removal of the neomycin cassette in the germline. (J:340171)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count