The targeting construct inserted a CAG-loxP-CAT-FRT-PGK-neo-FRT-loxP-AKR1C3-pA cassette into the locus. Cre-mediated recombination removed the cat reporter gene and selection cassette. (J:104881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count