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A DNA construct expressing the ectodomain of the human IL-4 receptor (residues 1-198 of the mature alpha-subunit of the receptor) and residues 473 to 610 of the human GP Ibalpha mature subunit (GP1BA) was inserted downstream of a 3-kb human GP Ibalpha (GP1BA) promoter cassette. Transgenic mouse lines Tg33 and Tg51 express surface fusion protein and were chosen for further studies. (J:131497)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
