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EN
The targeted allele is created to have an inverted exons 8-10 ((Ensemble ID: ENSMUSE00001223455, ENSMUSE00000400411, ENSMUSE00000335250, and introns) flanked with the FLEx cassette (inward-facing lox2272:loxP sites), followed by a FRT-flanked neomycin resistance cassette. The inversion creates a reading frame shift resulting in a null allele. Flp-mediated recombination removes the neo cassette. (J:339639)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
