The transgene contains the human skeletal actin promoter, mouse SLK mutated gene (upstream of full-length kinase-inactive SLK bearing a point mutation at lysine 63), and HA (hemagglutinin) tag sequence. Line 654 and 3405 Tg mice have a high and low expression level of K63R, respectively. (J:339424)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count