The transgene consists of the human COL2A1 promoter (the first ~4.5 kb upstream of transcription site), the beta-galactosidase reporter gene and COL2A1 intron 1. The promoter was used to drive expression of the transgene in differentiating chondrocytes. (J:80223)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count