CRISPR/Cas9 technology was used to replace the start codon of the carbonic anhydrase 4 (Car4) gene with a Cre-ERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain). (J:345362)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count