Log In|Sign Up
EN
This allele was generated at The Centre for Phenogenomics by injecting Cas9 mRNA with a guide RNA with the spacer sequence AGCATCTGACACTGAGTAAGand a single-strand oligonucleotide encoding the changes c.1376_1377CA>TC (p.S459F) and a silent mutation c.1368C>T (p.A456) to disrupt the protospacer adjacent motif (PAM) sequence. (J:339146)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
