A targeting vector is designed to insert an internal ribosome entry site (IRES), tdTomato fluorescent protein, and bovine growth hormone polyadenylation sequence, followed by an loxP-flanked neomycin resistance cassette, downstream of exon 2. Cre-mediated recombination removed the neo cassette. (J:279686)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count